The Constitution of the Republic of Uganda emphasizes the independence of the Human Rights Commission while performing its duties. It is vital that the commission in performing its duties is not subject to the direction or control of any person or authority to avoid conflict of interest and to make irrational decisions. The notion of human rights is very sensitive and therefore when concluding in regards to whether there is a violation, the Judges in the matter must not be clouded in judgement by way of control by any person or authority.

In addition to this, while performing its duties, the commission shall be self-accounting and all the administrative expenses of the commission, including salaries, allowances and pensions payable to persons serving with the commission, shall be charged on the consolidated fund.

To ensure the principles of checks and balances apply,  Parliament has the power to prescribe the salaries and allowances to be paid to the chairperson and other members of the commission.

In regards to the tenure of commissioners holding this office, the Constitution provides for removal to the extent that the removal of a commissioner shall be in accordance with the procedure for the removal of a Judge of the High Court with the necessary modifications. Also, any recruitments concerning the commission with regards to employment must be made in consultation with the public service commission.

In conclusion, the Constitution goes ahead to give powers to the parliament, which is the law-making the body to make laws to regulate and facilitate the performance of the functions of the Uganda Human Rights Commission.